Hemopoietic stem-cell compartment of the SCID mouse: double-exponential survival curve after gamma irradiation.

Attempts at identification of hemopoietic stem cell in mouse.

P-60: Survival Assessment of Mouse In Vitro Embryos after Exposure to Cell Phone Radiation

Background Using cellular phone among adults, teenagers and children has rapidly increased all over the world. Also, the concern on the possible health hazards of Electromagnetic Fields (EMF) induced from cell phones on reproduction has been growing in many countries. The aim was to assess the morphological parameters, survival rate and development of mouse in-vitro embryos obtained by natural ...

Cyclic ADP-ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice.

Cyclic ADP-ribose (cADPR) is a potent and universal intracellular calcium mobilizer, recently shown to behave as a new hemopoietic cytokine stimulating the in vitro proliferation of both committed and uncommitted human hemopoietic progenitors (HP). Here, we investigated the effects of cADPR on engraftment of hemopoietic stem cells (HSC) into irradiated NOD/SCID mice. Two different protocols wer...

Differentiation of Mouse Embryonic Stem Cell into Insulin-Secreting Cell

Purpose: Differentiation of mouse embryonic stem cells into Insulin secreting endocrine cells. Materials and Methods: In this study, Royan B1 mouse embryonic stem cell (derived from C57BL/6 mouse) were used. In directed differentiation method, embryonicstem cells after embryoid bodies formation were differentiated into insulin secreting cells. Nestin positive cells were obtained after culture ...

Depletion of Ovarian Primordial Follicles after Gamma Irradiation

Introduction:Artifical sourace of radiation have increased worldwide average annual exposure of mankind and could especially affect rapidly dividing cells in gonads. Since, radiation sensitivities of different components of primordial follicles, and the time required for their deplation have not been morphologically eatablished we decided to estimate the time required for depletion of primordi...